99%+ Purity
COA Included
Sealed Vials
FOXO4-DRI
Senolytic peptide for cellular rejuvenation
Senescent cell apoptosis
Key Benefits
- May support selective senescent cell elimination
- Research suggests enhanced cellular cleanup processes
- Potentially reduces age-related inflammatory factors
- Advanced stability through D-retro-inverso modification
- Selective targeting of problematic cellular populations
- May support tissue rejuvenation mechanisms
- Research indicates improved cellular health markers
Turn Back Your Cellular Clock at the Source
Your body accumulates damaged, inflammatory cells over time—they stick around causing problems instead of dying off naturally. This peptide specifically targets those problematic cells for elimination while leaving healthy tissue alone. It's like having a molecular cleanup crew that only goes after the troublemakers dragging down your recovery, energy, and overall vitality.
Senescent cell apoptosis / FOXO4-p53 disruption pathway
About FOXO4-DRI
FOXO4-DRI is a precision-engineered senolytic peptide that selectively eliminates senescent cells—the damaged, inflammatory cells that accumulate with age and stress. By disrupting the survival mechanisms these problematic cells use to avoid natural death, it helps restore your body's cellular environment to a more youthful state.
Who It's For
Ideal for individuals focused on longevity optimization, recovery enhancement, and addressing age-related decline at the cellular level. This represents a targeted approach to biological aging rather than just managing symptoms. Best integrated into comprehensive anti-aging protocols where cellular renewal and inflammatory reduction are primary goals.
Research Background
Cellular senescence represents a critical biological process where cells permanently stop dividing while remaining metabolically active, often in response to stress, DNA damage, or normal aging. While senescence initially serves as a protective mechanism against cancer, senescent cells accumulate over time and secrete harmful inflammatory factors collectively known as the senescence-associated secretory phenotype (SASP). This accumulation contributes to numerous age-related diseases including arthritis, cardiovascular disease, diabetes, and neurodegeneration.
FOXO4-DRI research focuses on selective elimination of these problematic senescent cells through a process called senolysis. The primary mechanism involves disrupting the survival pathways that allow senescent cells to resist natural cell death, specifically targeting the FOXO4-p53 protein interaction that helps senescent cells evade apoptosis. By restoring the normal death pathways in these cells, FOXO4-DRI may help rejuvenate tissues and reduce age-related inflammation, potentially addressing multiple age-related conditions simultaneously through this targeted approach to cellular cleanup.
Dosing Protocol
| Level | Dose | |
|---|---|---|
Intermediate | 5 mg 1x/wk | |
Advanced | 10 mg 1x/wk | |
Maximum | 10 mg 2x/wk |
Select a dosing level and click Calculate to plan your protocol.
Vials Required
6
60.0 mg needed ÷ 10 per vial
Total Investment
$1050
$175.00 per vial
Per Dose
0.50 mL
50 units on U-100 syringe
Doses per Vial
2
10 ÷ 5.00 mg/dose
* Calculations based on standard reconstitution protocols. Consult research guidelines for specific applications.
Compliance & Disclaimer
This product is intended for laboratory research purposes only. Not for human consumption. All products are sold with the understanding that the purchaser will comply with all applicable local, state, and federal laws regarding the purchase and use of research chemicals. Certificate of Analysis available upon request.
FOXO4-DRI
$175.00