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99%+ Purity

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Sealed Vials

MOTS-c

Mitochondrial peptide for metabolic regulation

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$29.00

Injectable

SKU: MOTSC-10MG

AMPK activation

Key Benefits

May support enhanced glucose metabolism
Research suggests improved fat burning capacity
May promote mitochondrial function optimization
Could support improved insulin sensitivity
May enhance exercise performance and endurance
Research indicates potential metabolic flexibility benefits
May support healthy aging processes

Turn Your Body Into a Fat-Burning Machine That Never Crashes

Most metabolic boosters work for a few weeks, then your body adapts and you're back where you started—or worse. MOTS-c rewires your cellular energy systems at the mitochondrial level, so you keep burning fat efficiently without the inevitable metabolic slowdown. It's like having the metabolism of someone who's been lean their whole life.

Mitochondrial metabolism / AMPK activation pathway (glucose utilization, fatty acid oxidation)

About MOTS-c

MOTS-c is a mitochondrial-derived peptide that activates AMPK, your body's master energy sensor, to optimize how your cells burn fuel. It enhances glucose uptake in muscle tissue while simultaneously promoting fat oxidation, creating a metabolic environment where your body preferentially burns stored fat for energy. The peptide essentially reprograms cellular metabolism to function more efficiently, similar to the effects seen with intense exercise or caloric restriction.

Who It's For

Ideal for individuals struggling with metabolic flexibility, stubborn fat loss, or declining energy efficiency as they age. MOTS-c addresses the root cause of metabolic dysfunction by restoring mitochondrial communication pathways that naturally decline over time. This makes it particularly valuable in longer-term body composition protocols where maintaining metabolic rate and insulin sensitivity are crucial for sustained results.

Research Background

MOTS-c represents a fascinating example of mitochondrial-encoded peptides that act as metabolic regulators. This 16-amino-acid peptide functions as a cellular messenger, communicating between mitochondria and other cellular components to optimize energy metabolism. Research has primarily focused on two key areas: 1) AMPK-mediated metabolic reprogramming where MOTS-c activates the body's master energy sensor to improve glucose utilization and fat burning, and 2) longevity and healthspan enhancement through mechanisms that mimic the beneficial effects of exercise and caloric restriction. The peptide essentially acts as a metabolic switch, redirecting cellular energy production toward more efficient pathways while reducing inflammatory processes associated with aging. Studies suggest that MOTS-c levels naturally decline with age, potentially contributing to metabolic dysfunction in older individuals. Current research focuses on understanding optimal dosing strategies, identifying the most responsive patient populations, and exploring its potential as an anti-aging therapeutic. The peptide's ability to enhance exercise performance while improving metabolic health has generated significant interest in both therapeutic and performance enhancement applications.

Dosing Protocol

Reference dosing and protocol planning

Level	Dose	Frequency	Notes
Beginner	5 mg/wk	Weekly	Initial dosing to assess tolerance
Intermediate	5 mg 2x/wk	2-3x/week	Standard protocol after tolerance established
Advanced	10 mg/wk	Weekly	Enhanced protocol for experienced researchers
Maximum	20 mg/wk	2-3x/week	Maximum therapeutic range

Default:Weekly

Timing:AM

Dilution:1 mL

Select a dosing level and click Calculate to plan your protocol.

Dosing Level

Protocol Duration

12 weeks

4 wk12 wk24 wk

2-3x/week(level-specific) (1.0 doses/week × 12 weeks = 12 total doses)

Selected vial: 10mg(10 mg per vial)

Vials Required

60.0 mg needed ÷ 10 per vial

Total Investment

$174

$29.00 per vial

Per Dose

0.50 mL

50 units on U-100 syringe

Doses per Vial

10 ÷ 5.00 mg/dose

* Calculations based on standard reconstitution protocols. Consult research guidelines for specific applications.

Educational Resources

Download educational materials and research documentation for MOTS-c.

Mots-c Overview

PDF Document

Download

Mots-c Cheat Sheet

PDF Document

Download

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Compliance & Disclaimer

This product is intended for laboratory research purposes only. Not for human consumption. All products are sold with the understanding that the purchaser will comply with all applicable local, state, and federal laws regarding the purchase and use of research chemicals. Certificate of Analysis available upon request.